BIO 234 01 HXAgenda:

Week

Introduction

Welcome beautiful people. The central dogma of genetics is central to the understanding of life. The amazing contemporary development of the instruments that facilitate both research and medicine should capture your interest and awe. This is truly a fun and engaging section. I hope yo enjoy it as much as I do.

Module Learning Outcomes

Chapter 11

I. The Functions of Genetic Material

Explain the two functions of the genome
Explain the meaning of the central dogma of molecular biology
Differentiate between genotype and phenotype and explain how environmental factors influence phenotype

II. DNA Replication

Explain the meaning of semiconservative DNA replication
Explain why DNA replication is bidirectional and includes both a leading and lagging strand
Explain why Okazaki fragments are formed
Describe the process of DNA replication and the functions of the enzymes involved
Identify the differences between DNA replication in bacteria and eukaryotes
Explain the process of rolling circle replication

III. RNA Transcription

Explain how RNA is synthesized using DNA as a template
Distinguish between transcription in prokaryotes and eukaryotes

IV. Protein Synthesis (Translation)

Describe the genetic code and explain why it is considered almost universal
Explain the process of translation and the functions of the molecular machinery of translation
Compare translation in eukaryotes and prokaryotes

V. Mutations

Compare point mutations and frameshift mutations
Describe the differences between missense, nonsense, and silent mutations
Describe the differences between light and dark repair
Explain how different mutagens act
Explain why the Ames test can be used to detect carcinogens
Analyze sequences of DNA and identify examples of types of mutations

VI. How Asexual Prokaryotes Achieve Genetic Diversity

Compare the processes of transformation, transduction, and conjugation
Explain how asexual gene transfer results in prokaryotic genetic diversity
Explain the structure and consequences for bacterial genetic diversity of transposons

VII. Gene Regulation: Operon Theory

Compare inducible operons and repressible operons
Describe why regulation of operons is important

Learning Activities

Activities

Reading: Chapters 11
Lab: Bacterial Transformation
- Rainbow plasmids

Assignments:

Assignment: Topic outline - one page
Discussion Board: Innate and Adaptive immune system
Quiz: 06

Resources

Textbook: Microbiology

Presentation: OpenStax_Microbiology_CH11_ImageSlideshow.pptx

Video:

BIO 234 01 HX 05.07.24
BIO 234 01 HX 05.09.24

Weekly Time Expectations

All times are approximate. Some activities may take less or more time. Please try to plan accordingly.

Reading: 45 minutes
Lab: 2 hours
Assignment: 45 minutes
Discussion Board: 45 minutes
Quiz: 45 minutes